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Three symptom pathways

Symptoms and When to Seek Care

A practical guide to urinary symptoms, knee osteoarthritis symptoms, and uterine fibroid symptoms—including warning signs.

Symptoms are the starting point

SoCal Interventional evaluates three distinct symptom pathways: urinary symptoms that may relate to an enlarged prostate, knee pain that may relate to osteoarthritis, and bleeding or pressure symptoms that may relate to uterine fibroids.

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Symptoms do not determine procedure candidacy. Similar symptoms can have different causes. The right diagnosis and a comparison of reasonable treatments come before PAE, GAE, or UFE.

Choose the relevant pathway

Three conditions, three separate evaluations

These procedures treat different conditions and are not interchangeable. Start with the symptoms that brought you here.

Patient discussing prostate artery embolization evaluation

Urinary symptoms

Enlarged prostate / BPH

Frequency, urgency, nighttime urination, weak flow, difficulty starting, straining, or incomplete emptying.

Review BPH symptoms

Adults walking comfortably during knee osteoarthritis care

Knee symptoms

Knee osteoarthritis

Activity-related pain, stiffness after rest, swelling, reduced motion, instability, or difficulty with stairs and walking.

Review knee symptoms

Patient discussing uterine fibroid treatment options

Pelvic and bleeding symptoms

Uterine fibroids

Heavy or prolonged periods, anemia, pelvic pressure, urinary frequency, constipation, pain, or abdominal enlargement.

Review fibroid symptoms

Pathway 1 · Urinary symptoms

Symptoms that may relate to BPH

Benign prostatic hyperplasia is a noncancerous enlargement of the prostate. Because the prostate surrounds part of the urethra, enlargement can contribute to lower urinary tract symptoms—but prostate size does not always match symptom severity.

PAE pathway

Frequent urination
Waking at night to urinate
Urgency or leakage before reaching a bathroom
Difficulty starting the stream
Weak, interrupted, or stop-and-start flow
Straining to urinate
Dribbling after urination
Feeling the bladder has not emptied

Evaluation may include

  • Symptom history, medication review, and validated questionnaire
  • Physical examination and urinalysis
  • Selected blood tests, urinary-flow testing, and post-void residual
  • Ultrasound, cystoscopy, or other urologic testing when indicated

Treatment discussion may include

  • Observation and lifestyle measures
  • Prescription medication
  • Office-based or surgical urologic procedures
  • Prostate artery embolization for appropriately selected patients
Symptoms may have another cause. Infection, bladder dysfunction, prostatitis, urethral narrowing, medication effects, neurologic disease, prostate cancer, and other conditions can produce similar symptoms.

Pathway 2 · Knee symptoms

Symptoms that may relate to knee osteoarthritis

Osteoarthritis involves changes in cartilage, bone, and the joint lining. Symptoms often begin gradually, and imaging findings do not always match the amount or source of pain.

GAE pathway

Pain with walking, stairs, standing, or other use
Stiffness after rest or in the morning
Swelling in or around the knee
Reduced bending or straightening
Grinding, clicking, or creaking sensations
Feeling loose, unstable, or likely to buckle
Night pain or disrupted sleep
Reduced walking or activity tolerance

Evaluation may include

  • History, physical examination, gait, alignment, and stability assessment
  • Weight-bearing X-rays and selected additional imaging
  • Laboratory or joint-fluid testing if infection, gout, or inflammatory arthritis is a concern
  • Review of the hip, spine, nerves, and circulation when symptoms suggest another source

Treatment discussion may include

  • Exercise, physical therapy, and activity modification
  • Weight management when relevant
  • Topical or oral medication and selected injections
  • Orthopedic surgery or, for selected patients, GAE
GAE does not regrow cartilage or correct joint structure. Evidence remains mixed, and knee pain from infection, fracture, instability, referred pain, or another diagnosis needs a different plan.

Pathway 3 · Bleeding, pressure, and pelvic symptoms

Symptoms that may relate to uterine fibroids

Fibroids are noncancerous growths arising from uterine muscle. Their number, size, and location help determine whether they plausibly explain symptoms and which treatments deserve consideration.

UFE pathway

Heavy, longer, or more frequent periods
Bleeding between periods or passing clots
Fatigue, dizziness, or shortness of breath from anemia
Pelvic pressure or abdominal fullness
Frequent urination or difficulty emptying the bladder
Constipation or rectal pressure
Pelvic, abdominal, or lower-back pain
Pain during sex or fertility concerns

Evaluation may include

  • Gynecologic history and examination
  • Blood count and iron studies when bleeding is heavy
  • Pelvic ultrasound and often MRI for procedural planning
  • Endometrial or other evaluation when abnormal bleeding requires it

Treatment discussion may include

  • Observation or medication
  • Uterine fibroid embolization
  • Myomectomy or hysterectomy
  • Focused ultrasound or another option in selected settings
Fertility goals change the decision. Pregnancy after UFE is possible, but comparative fertility evidence remains limited. Future pregnancy goals should be reviewed with gynecology and, when appropriate, a fertility specialist.
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Do not wait for an online appointment

When symptoms need prompt or emergency care

These examples are not exhaustive. Call 911 or seek emergency care for severe symptoms, fainting, chest pain, breathing difficulty, signs of stroke, or another medical emergency.

Urinary warning signs

  • Unable to urinate
  • Blood or clots in the urine
  • Fever or chills with urinary symptoms
  • Severe lower-abdominal or urinary pain

Knee or leg warning signs

  • A hot, red, very swollen joint with fever
  • Major injury, deformity, or inability to bear weight
  • A cold, pale, numb, or suddenly weak foot
  • Calf swelling with chest pain or shortness of breath

Bleeding or pelvic warning signs

  • Heavy bleeding with fainting, chest pain, or shortness of breath
  • Severe sudden pelvic or abdominal pain
  • Fever with pelvic pain or foul discharge
  • Bleeding or severe pain during pregnancy

Diagnosis first

A useful evaluation answers four questions

The same disciplined process applies to all three pathways even though the specialists and tests differ.

What is the symptom pattern?

Clarify onset, triggers, severity, progression, and the effect on sleep, work, mobility, and daily life.

What is the likely cause?

Use history, examination, and appropriate testing to distinguish the suspected condition from other diagnoses.

What has already been tried?

Review medication, therapy, procedures, imaging, specialist care, response, side effects, and remaining goals.

Which trade-off fits?

Compare expected benefit, uncertainty, recovery, risks, durability, alternatives, and the possibility of later treatment.

Where interventional radiology may fit

PAE, GAE, and UFE are options—not diagnoses

A consultation is intended to determine whether a procedure belongs in the discussion, not to guarantee that one will be recommended.

PAE for selected BPH symptoms

A catheter-based treatment that reduces selected prostate blood flow. Symptom improvement is variable, and some urologic operations provide stronger objective urinary outcomes.

Understand PAE →

GAE for selected knee OA pain

An evolving symptom-management procedure intended to reduce selected abnormal blood flow near an inflamed knee lining. It does not cure arthritis, and controlled evidence is mixed.

Review GAE →

UFE for selected fibroid symptoms

A uterus-preserving treatment that reduces fibroid blood flow. Recovery, fertility goals, ovarian effects, and the possibility of later treatment require individual discussion.

Explore UFE →

Patient information and guidance

Authoritative resources

NIDDK: Enlarged prostate

Official patient information about BPH symptoms, complications, diagnosis, and treatment.

Visit NIDDK →

NIAMS: Osteoarthritis

Official information about osteoarthritis symptoms, diagnosis, and treatment.

Visit NIAMS →

ACOG: Uterine fibroids

Patient guidance about fibroid symptoms, evaluation, complications, and treatment choices.

Visit ACOG →

ACOG: Uterine artery embolization

Patient guidance about embolization, recovery, risks, fertility questions, and possible reintervention.

Review the UFE guidance →

Request an individualized symptom evaluation

SoCal Interventional provides consultations in Van Nuys and Irvine for people who want to understand whether PAE, GAE, UFE, or another treatment path should be considered.

Medical content reviewed July 2026. This page provides general education and is not a diagnosis or individual treatment recommendation.